About Astellas:
At Astellas we are a progressive health partner, delivering value and outcomes where needed.
We pursue innovative science, focusing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions.
We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage.
Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division.
We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes.
Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care.
The Opportunity:
As a Global Precision Medicine Lead, you’ll shape and deliver biomarker and diagnostic strategies that help bring truly personalised therapies to patients around the world. You’ll lead the development of companion diagnostics from concept to regulatory approval, working closely with external diagnostic partners and cross-functional teams.
This role is ideal for someone with deep expertise in applied biomarker research and diagnostic development — and the drive to turn scientific insight into real-world impact. You’ll be at the forefront of innovation, helping to define how precision medicine improves outcomes and transforms patient care.
Hybrid Working:
At Astellas we recognise the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimise the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.
Key Responsibilities for this Role:
- Participating and contributing to the development and execution of precision medicine and diagnostic strategies across early- and late-stage clinical programs in oncology and other therapeutic areas.
- Contributing and collaborating on the design of clinical studies incorporating patient stratification, enrichment, and biomarker testing, while supporting and developing study and regulatory documentation.
- Enhancing and advancing early drug development by implementing precision medicine strategies that define the relationship between biomarkers, efficacy, and safety.
- Facilitating and overseeing biomarker testing of patient samples and analyzing and interpreting clinical data to guide precision medicine strategies and support health authority submissions.
- Leading and managing the evaluation and selection of diagnostic technologies and external diagnostic partners to strengthen drug development programs.
- Integrating and aligning companion diagnostic studies with clinical programs from development through to approval, collaborating and coordinating with cross-functional teams and external partners.
- Ensuring and maintaining compliance with regulatory requirements for diagnostic tests and precision medicine approaches used in clinical studies.
- Representing and advising as a subject matter expert on cross-functional diagnostic teams for late-stage assets, driving and supporting successful diagnostic launches.
- Supporting and contributing to the publication and communication of findings from precision medicine research studies.
Required Experience:
- Proven experience and proven track record in the application of biomarkers and precision medicine in drug development at a biotech/pharmaceutical company.
- Solid understanding of clinical development strategies, clinical study design and companion diagnostic development is required.
- Experience in leading the implementation and interpretation of biomarker /diagnostic testing in clinical studies is required.
- Experience working in cross functional matrixed work environments is essential.
- Excellent communication, project management and leadership skills.
Preferred Experience:
- Experience in the registration of companion diagnostics and pharmaceuticals is preferred.
- Strong knowledge of the process and global regulations for companion diagnostic development, approval and launch.
Education:
- Advanced science degree (PhD, PharmD or MD) in a relevant scientific field or equivalent.
Additional Information:
- The is a permanent full-time position based in the UK.
- This position follows our hybrid working model. Role requires a blend of home and minimum of 1 day a quarter in office. Flexibility may be required in line with business need. Candidates must be located within a commutable distance of the office.
We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Beware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. If you encounter a fake profile or anything suspicious, report it promptly to LinkedIn's support team through LinkedIn Help.
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